Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11051)
Related Products (11051)
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Hypoxanthine-13C5
0 ImagesSynonyms: Purin-6-ol-13C5; Sarcine-13C5Hypoxanthine-13C5 is a 13C-labeled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
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Upadacitinib-15N,d2
0 ImagesCat. No.: HY-W727879Purity: 98.92%Synonyms: ABT-494-15N,d2Upadacitinib-15N,d2 (ABT-494-15N,d2) is the deuterium-labeled Upadacitinib (HY-19569). Upadacitinib-15N,d2 (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib-15N,d2 (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib-15N,d2 (ABT-494) can be used for several autoimmune disorders research.
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D-Leucine-d10
0 ImagesSynonyms: (R)-Leucine-d10D-Leucine-d10 is the deuterium labeled D-Leucine. D-Leucine is a more potent anti-seizure agent than L-leucine. D-leucine potently terminates seizures even after the onset of seizure activity. D-leucine, but not L-leucine, reduces long-term potentiation but had no effect on basal synaptic transmission in vitro.
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Methoxyamine-d3 Hydrochloride
0 ImagesSynonyms: O-Methylhydroxylamine-d3 hydrochlorideMethoxyamine-d3 (O-Methylhydroxylamine-d3) hydrochloride is the deuterium labeled Methoxyamine hydrochloride. Methoxyamine hydrochloride is an orally active and potent base excision repair (BER) inhibitor.
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Guanosine triphosphate-13C10 dilithium
0 ImagesCat. No.: HY-113225S5Purity: 99.4%Synonyms: GTP-13C10 dilithiumGuanosine triphosphate-13C10 (GTP-13C10) dilithium is 13C-labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate dilithium (GTP) is a critical nucleotide and regulator of cellular metabolism. Guanosine triphosphate dilithium promotes ribosomal DNA localization, pre-rRNA transcription and ribosome biogenesis by binding to RNA polymerase I and GPN proteins (GPN1/3). Guanosine triphosphate dilithium links MYC-dependent ribosome biogenesis to nucleotide sufficiency, acts as a metabolic gatekeeper supporting protein synthesis, DNA/RNA synthesis and cellular signal transduction, while also participating in the physiological activities of pancreatic β-cells and serving as an oxidative substrate for reactive oxygen species. In small cell lung cancer with high MYC expression, Guanosine triphosphate dilithium accumulates through the IMPDH-driven synthetic pathway, thereby affecting apoptosis and mitotic processes. Guanosine triphosphate dilithium is used in the research of small cell lung cancer, hepatoblastoma and cellular metabolism.
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Choline-d13 chloride
0 ImagesCholine-d13 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
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Indole-3-pyruvic acid-d5
0 ImagesCat. No.: HY-W718300CAS No.: 85163-57-1Indole-3-pyruvic acid-d5 is deuterated labeled Indole-3-pyruvic acid. Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety.
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Myristic acid-d3
0 ImagesMyristic acid-d33 is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.
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N6-Methyladenosine-13C
0 ImagesSynonyms: 6-Methyladenosine-13C; N-Methyladenosine-13CN6-Methyladenosine-13C is the 13C labeled isotope of N6-Methyladenosine.
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3-Methoxy-4-hydroxyphenylglycol-d3
0 ImagesSynonyms: HMPG-d3; MHPG-d3; MOPEG-d33-Methoxy-4-hydroxyphenylglycol-d3 (HMPG-d3) is the deuterium labeled 3-Methoxy-4-hydroxyphenylglycol. 3-Methoxy-4-hydroxyphenylglycol is a metabolite of norepinephrine degradation in the brain. 3-Methoxy-4-hydroxyphenylglycol (HMPG) serves as an indicator of noradrenergic activity in the central nervous system. 3-Methoxy-4-hydroxyphenylglycol (HMPG) can be used for research on diseases such as depression and chronic schizophrenia.
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Glycerol-d8
0 ImagesSynonyms: 1,2,3-Propanetriol-d8; Glycerin-d8Glycerol-d8 is the deuterium labeled Glycerol.
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DL-Dithiothreitol-d6
0 ImagesSynonyms: DTT-d6DL-Dithiothreitol-d6 is the deuterated form of DL-Dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond.
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DL-Cystine-d6
0 ImagesDL-Cystine-d6 is the deuterium labeled DL-Cystine (HY-W013940). DL-Cystine is a cysteine derivative.
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4-Methyl-2-oxopentanoic acid-13C sodium
0 ImagesSynonyms: α-Ketoisocaproic acid-13C sodium4-Methyl-2-oxopentanoic acid-13C (sodium) is the 13C labeled 4-Methyl-2-oxopentanoic acid sodium.
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Benzophenone-d10
0 ImagesBenzophenone-d10 is the deuterium labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity.
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D-Panthenol-d4
0 ImagesD-Panthenol-d4 is the deuterium labeled D-Panthenol.
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Docosanoic acid-d3
0 ImagesSynonyms: Behenic acid-d3Docosanoic acid-d3 (Behenic acid-d3) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans.
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β-Sitosterol-d7 (Mixture of Diastereomers)
0 Imagesβ-Sitosterol-d7 (Mixture of Diastereomers) is the deuterium labeled β-Sitosterol (mixture of diasteromers).
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Resiquimod-d5
0 ImagesSynonyms: R848-d5; S28463-d5Resiquimod-d5 is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.
